Ministry of Health warns about high Ibuprofen doses

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THE Ministry of Health of Spain has released a document warning about the high cardiovascular risk associated with taking large doses of Ibuprofen and Dexibuprofen.

The Medicines and Sanitary Products Agency of Spain (AEMPS) has recommended health care professionals not to prescribe high doses of these medicines to patients with severe cardiovascular pathologies, such as cardiac insufficiency, coronary heart disease or cerebrovascular disease.

Clinical studies have confirmed that the intake of high doses of Ibuprofen (more than 2,400 milligrams per day) and Dexibuprofen (more than 1,200 milligrams per day), are associated with a higher risk of thrombosis.


The Ministry of Health explained that it is advisable to take the lowest doses possible during the shortest period of time necessary to control the symptoms.

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