Moderna begins clinical trials of HIV vaccine

Share

The pharmaceutical giant Moderna has begun clinical trials of a new HIV vaccine using mRNA technology.
On January 27, the scientific research organisation IAVI and the pharmaceutical company Moderna announced that they have teamed up to launch the first phase of clinical trials on experimental vaccines against HIV using mRNA technology.
The trial is designed to test the hypothesis that the sequential administering of HIV immunogens via messenger RNA can trigger specific types of responses from B cells, leading to the generation of broadly neutralising antibodies (bNAbs).
The generation of bNAbs is one of the objectives of vaccination against HIV, and this is the first step in the process. The immunogens that are being tested in the trials were developed by scientific teams from IAVI and Scripps Research and will be given via mRNA technology from Moderna.
The study will be carried out at four centres in the United States. The centres will enroll 56 HIV-negative adult volunteers, of whom 48 will receive one or two doses of mRNA-1644 and 32 will receive the mRNA-1644v2-Core booster. Another eight volunteers will only receive the booster immunogen.
The immune responses from the participants will be studied in molecular detail in order to evaluate whether the desired results were achieved. The safety of the participants will also be monitored for six months after the last vaccine is given.
“We believe that mRNA offers a unique opportunity to address critical unmet public health needs around the world,” said Stephen Hoge, president of Moderna.
The CEO of IAVI, Mark Feinberg, also said: “the search for an HIV vaccine has been long and challenging, and having new tools in terms of immunogens and platforms could be the key to making rapid progress toward an urgently needed, effective HIV vaccine”.
________________________________________________________________________
Thank you for taking the time to read this article, do remember to come back and check The Euro Weekly News website for all your up-to-date local and international news stories and remember, you can also follow us on Facebook and Instagram.

Tamsin Brown

Originally from London, Tamsin is based in Malaga and is a local reporter for the Euro Weekly News covering Spanish and international news. Got a news story you want to share? Then get in touch at editorial@euroweeklynews.com.



Recent Posts

  • World News

Russia considers leaving WHO and WTO amongst other World organisations

On Tuesday, May, 17, it was reported that Russia's Foreign Ministry had sent proposals to…

27 mins ago
  • UK News

Explosion rips through block of flats in Skelmersdale Lancashire injuring 5

At least five people were injures in an explosion that ripped through a block of…

45 mins ago
  • World News

Shock as beloved basketball star Ademola Okulaja dies aged 46

Ademola Okulaja died in Berlin on Tuesday, May, 17, at the age of 46 as…

1 hour ago
  • Spain

Emir of Qatar announces €4,720 million investment into Spain

On the evening of Tuesday, May, 17, the Emir of Qatar, Tamim bin Hamad Al…

2 hours ago
  • World News

Police detain over 400 protestors in Yerevan Armenia following Azerbaijan dispute

On Tuesday, May, 17, anti-government protests in Yerevan Armenia following the territorial dispute of the…

2 hours ago
  • Ukraine crisis

Putin on Russian oil sanctions claims West fostered Ukraine’s “neo-Nazism”

On Tuesday, May, 17, the Kremlin published an official press release on an oil industry…

3 hours ago