Spanish-UK research sees mental health breakthrough

New hope for mental health patients

Image illustrating medical research. Credit: SmartPhotoLab/

A collaborative study between Spain and the United Kingdom has resulted in effective results for the most serious of mental health conditions.

Recently, a joint research effort revealed the efficacy of paliperidone, a second-generation antipsychotic, in a ground-breaking study.

Participants included Juan Antonio Garcia-Carmona, a neurologist at Santa Lucia Hospital in Cartagena, and Pilar Campos Navarro, a psychiatrist at the same facility, alongside teams from various medical centres including the Imperial College of London.

A leap in psychiatric management

The study has put paliperidone under the spotlight for its potential to manage psychotic breaks with just two annual injections.

This novel approach was preferred by 43 per cent of the participants for its minimal administration frequency, according to Garcia-Carmona and Campos Navarro. ’43 per cent of patients indicated their preference for treatment with fewer administrations as the main reason for switching to semi-annual paliperidone,’ reports Telecinco.

Enhanced treatment

The adherence rate to the semi-annual injection plan was remarkably high, reaching 94 per cent after six months. This figure significantly surpasses that of other injectable schizophrenia treatments.

Such a high adherence rate underscores the treatment’s potential to transform patient management in this area.

Pioneering research

The research, detailed in ‘Therapeutics Advances in Pharmacology’, is not only pioneering in its approach but also comprehensive in scope.

Set to conclude in 2025, the final report will assess quality of life, patient self-perception, and metabolic impacts. This broad spectrum of analysis promises to offer a holistic view of the treatment’s benefits and potential side effects.

Schizophrenia, affecting around half a million people in Spain alone, remains one of the most challenging mental health disorders.

Characterised by severe symptoms such as delusions, hallucinations, and thought disturbances, it significantly impacts a patient’s quality of life.

The study’s findings offer a beacon of hope for those living with this condition, suggesting a shift towards more manageable and less frequent treatment procedures.

This collaboration between Spanish and British researchers underscores the importance of international cooperation in advancing medical science and patient care.

As the study progresses, its findings could pave the way for a new standard in the treatment of schizophrenia and related disorders, marking a significant step forward in mental health care.

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Written by

John Ensor

Originally from Doncaster, Yorkshire, John now lives in Galicia, Northern Spain with his wife Nina. He is passionate about news, music, cycling and animals.